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J Am Coll Cardiol, 2004; 44:2301-2306, doi:10.1016/j.jacc.2004.09.040
© 2004 by the American College of Cardiology Foundation
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Prevention of lesion recurrence in chronic total coronary occlusions by paclitaxel-eluting stents

Gerald S. Werner, MD, FACC*, Andreas Krack, MD, Gero Schwarz, MD, Dirk Prochnau, MD, Stefan Betge, MD and Hans R. Figulla, MD

Clinic for Internal Medicine I, Friedrich-Schiller University Jena, Jena, Germany



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  		Figure 1 Cumulative distribution of minimum luminal diameter after procedure and at follow-up with paclitaxel-eluting (Taxus) and bare metal stents (BMS). Open squares = post-procedure Taxus; open circles = follow-up Taxus; solid squares = post-procedure BMS; solid circles = follow-up BMS.

 


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  		Figure 2 Examples from the Taxus group. (A) Occlusion location indicated by arrowhead; (B) after stent implantation (stents indicated by arrows); (C) follow-up. Patient 1 (age 59 years, male) right coronary artery (RCA) occlusion (duration nine months), three stents (total length 72 mm). Patient 2 (age 51 years, male) left anterior descending coronary artery (LAD) occlusion (seven months), one 28-mm stent. Moderate positive remodeling at follow-up (C, arrowhead). Patient 3 (age 74 years, female, diabetes) ostial LAD occlusion (eight months), two stents (total length 44 mm). Patient 4 (age 54 years, male, diabetes) RCA occlusion, one 28-mm stent. (C) Irregular moderate positive remodeling at follow-up (arrow) and focal restenosis proximal (arrowhead). After additional Taxus stent, no recurrence four months later, no progression of the negative remodeling (D, arrow).

 


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  		Figure 3 Kaplan-Meier curves of major adverse cardiac event (MACE)-free survival; p value for log-rank comparison of Taxus and bare metal stent (BMS) groups.

 




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