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Safety and efficacy of intravenously administered tedisamil for rapid conversion of recent-onset atrial fibrillation or atrial flutter

Stefan H. Hohnloser, MD^*,*, Paul Dorian, MD, Matthias Straub, MD, Katrin Beckmann and Peter Kowey, MD

^* J. W. Goethe University, Frankfurt, Germany
St. Michel's Hospital, Toronto, Canada
Solvay Pharmaceuticals GmbH, Hannover, Germany
Lankenau Hospital and the Main Line Health System, Wynnewood, Pennsylvania, USA

View larger version (23K): [in a new window]   Figure 1 Cumulative incidence of drug-associated conversion to normal sinus rhythm (NSR) within the first 2.5 h after drug administration in patients with atrial fibrillation (Afib) or atrial flutter (Aflu) and in the entire patient population. Numbers in parentheses indicate patients treated.

View larger version (18K): [in a new window]   Figure 2 Kaplan-Meier estimates for time to first conversion to normal sinus rhythm (NSR) in patients presenting with atrial fibrillation.