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Genotypes associated with myocardial infarction risk are more common in African Americans than in European Americans

David E. Lanfear, MD^*, Sharon Marsh, PhD^*, Sharon Cresci, MD^*, William D. Shannon, PhD^*, John A. Spertus, MD, FACC and Howard L. McLeod, PharmD^*,*

^* Washington University School of Medicine, Departments of Medicine, Genetics, Molecular Biology, and Pharmacology, and Division of Biostatistics, St. Louis, Missouri, USA
Mid America Heart Institute-University of Missouri Kansas City, Kansas City, Missouri, USA

View larger version (47K): [in a new window]   Figure 1 Frequency (%) of compound risk-associated genotypes in African-American (AA) and European-American (EA) subjects with complete genotype information (n = 91 for EA, n = 88 for AA). GJA4 = connexin-37; MMP3 = stromelysin-1; PAI-1 = plasminogen activator inhibitor-1.