Obesity and suppressed B-type natriuretic peptide levels in heart failure
Mandeep R. Mehra, MD, FACC*,*,
Patricia A. Uber, PharmD*,
Myung H. Park, MD*,
Robert L. Scott, MD*,
Hector O. Ventura, MD, FACC*,
Bobbett C. Harris, RN* and
Edward D. Frohlich, MD, FACC*
* Department of Cardiovascular Medicine, Ochsner Clinic Foundation, New Orleans, Louisiana, USA
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Figure 1 (A) Obese patients have lower circulating levels of B-type natriuretic peptide (BNP) compared with both lean and overweight patients with heart failure. (B) Difference in circulating levels of BNP in obese and nonobese patients (lean and overweight).
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Figure 2 This figure depicts the raw data demonstrating a significant inverse correlation between circulating B-type natriuretic peptide (BNP) levels and body mass index (BMI).
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Figure 3 No difference in emergency department visits, heart failure hospitalization, or death between obese (triangles) and nonobese (circles) patients at 12-month follow-up was noted in the obese and nonobese patients with heart failure.
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