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Outcomes in cardiac transplant recipients using allografts from older donors versus mortality on the transplant waiting list

Implications for donor selection criteria

Katherine Lietz, MD, PhD^*, Ranjit John, MD^*,*, Donna M. Mancini, MD and Niloo M. Edwards, MD^*

^* Cardiothoracic Surgery, New York, New YorkUSA
Cardiology, Columbia Presbyterian Medical Center, Columbia University, New York, New York, USA

View larger version (19K): [in a new window]   Figure 1 Kaplan-Meier survival after heart transplantation by donor age. Overlapping squares (top) = donor age 40 years (n = 346); triangles = donor age 40 to 50 years (n = 97); circles = donor age >50 years (n = 36).

View larger version (20K): [in a new window]   Figure 2 Kaplan-Meier (A) freedom from transplant-related coronary artery disease (TCAD) and (B) hazard function for the presence of TCAD, as detected by annual coronary angiography. Squares = donor age 30 years (n = 169); triangles = donor age >30 years (n = 132).

View larger version (23K): [in a new window]   Figure 3 Kaplan-Meier survival from enrollment on waiting lists for (A) status I and (B) status II patients.