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Clinical efficacy of sildenafil in primary pulmonary hypertension

A randomized, placebo-controlled, double-blind, crossover study

^* Department of Cardiology, CARE Hospital, Hyderabad, India

View larger version (22K): [in a new window]   Figure 1 Change in exercise time during the study in placebo-first group (n = 12). The y-axis shows time spent on treadmill, using Naughton Protocol, in seconds. p = 0.83 for baseline versus end of placebo phase; p < 0.001 for end of placebo phase to end of sildenafil phase.

View larger version (21K): [in a new window]   Figure 2 Change in exercise time during the study in sildenafil-first group (n = 10). The y-axis shows time spent on treadmill, using Naughton protocol, in seconds. p 0.005 for baseline versus end of sildenafil phase, for end of sildenafil versus end of placebo phase, and for baseline versus end of placebo.