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Aspirin dose and six-month outcome after an acute coronary syndrome

Martin J. Quinn, MD, PhD^*, Herbert D. Aronow, MD, MPH, Robert M. Califf, MD, FACC, Deepak L. Bhatt, MD, FACC, Shelly Sapp, MS, Neal S. Kleiman, MD, FACC^||, Robert A. Harrington, MD, FACC, David F. Kong, MD, AM, David E. Kandzari, MD and Eric J. Topol, MD, FACC^,*

^* St. Vincents University Hospital, Dublin, Ireland
Division of Cardiovascular Medicine, Hospital of the University of Pennsylvania and Philadelphia Veterans Administration Medical Center, Philadelphia, Pennsylvania, USA
Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, Cleveland, Ohio, USA
The Duke Clinical Research Institute, Durham, North Carolina, USA
^|| Baylor College of Medicine, Houston, Texas, USA

View larger version (15K): [in a new window]   Figure 1 Distribution of aspirin doses in the GUSTO IIb and PURSUIT trials.

View larger version (13K): [in a new window]   Figure 2 Multivariate adjusted hazard ratios for six-month death, non-fatal myocardial infarction (MI), and stroke. CI = confidence interval.

View larger version (12K): [in a new window]   Figure 3 Hazard ratios for six-month death, non-fatal myocardial infarction (MI), and stroke after matching on the basis of the propensity score. CI = confidence interval.