This Article Abstract Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Kontos, M. C. Articles by Jesse, R. L. Search for Related Content PubMed PubMed Citation Articles by Kontos, M. C. Articles by Jesse, R. L.

Implication of different cardiac troponin I levels for clinical outcomes and prognosis of acute chest pain patients

Michael C. Kontos, MD^*,*, Rakesh Shah, MD^*, Lucie M. Fritz, PhD, F. Philip Anderson, PhD, James L. Tatum, MD, Joseph P. Ornato, MD and Robert L. Jesse, MD, PhD^*

^* Department of Internal Medicine, Cardiology Division, Medical College of Virginia, Virginia Commonwealth University, Richmond, Virginia, USA
Department of Emergency Medicine, Medical College of Virginia, Virginia Commonwealth University, Richmond, Virginia, USA
Department of Pathology, Clinical Chemistry Division, Medical College of Virginia, Virginia Commonwealth University, Richmond, Virginia, USA
Department of Radiology, Medical College of Virginia, Virginia Commonwealth University, Richmond, Virginia, USA

View larger version (14K): [in a new window]   Figure 1 Kaplan-Meier curves of six-month cardiac mortality for the different cardiac troponin I (cTnI) values. The trend toward increased mortality and increased cTnI was highly significant (p < 0.001). In addition, mortality was significantly different (p < 0.01) between the negative (neg) cTnI and low, intermediate (inter), and high cTnI groups.

View larger version (44K): [in a new window]   Figure 2 Positive outcomes based on peak cardiac troponin I (cTnI) values. The trend toward an increased number of events for increasing peak cTnI values was highly significant (p < 0.001). *p < 0.001. #p < 0.02. Open bars = no troponin I; vertically striped bars = low troponin I; horizontally striped bars = intermediate troponin I; diagonally striped bars = high troponin I. MI = myocardial infarction; Revasc = revascularization; Sig Dz = significant disease.

View larger version (44K): [in a new window]   Figure 3 Positive outcomes based on peak cardiac troponin I (cTnI) values after excluding creatine kinase-MB myocardial infarction (MI) at the time of admission as an end point. The trend toward an increased number of events for increasing peak cTnI values was highly significant (p < 0.001). *p < 0.02. Open bars = no troponin I; vertically striped bars = low troponin I; horizontally striped bars = intermediate troponin I; diagonally striped bars = high troponin I. Revasc = revascularization; Sig Dz = significant disease.