Cardiovascular risk reduction in hypertensive black patients with left ventricular hypertrophy
The life study
Stevo Julius, MD*,*,
Michael H. Alderman, MD ,
Gareth Beevers, MD ,
Björn Dahlöf, MD ,
Richard B. Devereux, MD, FACC||,
Janice G. Douglas, MD¶,
Jonathan M. Edelman, MD#,
Katherine E. Harris, DrPH#,
Sverre E. Kjeldsen, MD**,
Shawna Nesbitt, MD ,
Otelio S. Randall, MD and
Jackson T. Wright, Jr, MD, PhD¶
* Department of Internal Medicine, Division of Hypertension, University of Michigan, Ann Arbor, Michigan, USA
Albert Einstein College of Medicine, Bronx, New York, USA
City Hospital, Birmingham, England, UK
Department of Medicine, Sahlgrenska University Hospital, Östra, Göteborg, Sweden
|| Division of Cardiology, Cornell Medical Center, New York, New York, USA
¶ Case Western Reserve University, Division of Hypertension, Cleveland, Ohio, USA
# Merck & Co., Inc., West Point, Pennsylvania, USA
** Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, and Department of Cardiology, Ullevaal University Hospital, Oslo, Norway, USA
 Department of Internal Medicine, Division of Hypertension, University of Texas Southwestern, Dallas, Texas, USA
 Howard University Hospital, General Clinical Research Center, Washington, DC, USA

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Figure 1 Results of primary composite end point by ethnic group. The dots represent the hazard ratio; dot size is proportional to the number of patients for each ethnic group, as shown to the left. The line through each dot corresponds to the 95% confidence interval.
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Figure 2 Results of primary composite end point by ethnic group in the U.S.: blacks versus non-blacks.
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Figure 3 Primary composite end point: unadjusted and adjusted for baseline covariates in U.S. blacks (triangles) versus non-blacks (squares). Symbols represent the hazard ratio; the line through each symbol corresponds to the 95% confidence interval. DBP = diastolic blood pressure; FRS = Framingham risk score; LVH = left ventricular hypertrophy; SBP = systolic blood pressure.
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Figure 4 Blood pressure results in the U.S.: blacks versus non-blacks.
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