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Glucose intolerance, as reflected by hemoglobin a_1c level, is associated with the incidence and severity of transplant coronary artery disease

Tomoko Kato, MD, PhD^*, Michael C. Y. Chan, MD, FRCPC, FACC^*, Shao-Zhou Gao, MD^*, John S. Schroeder, MD^*, Mitsuhiro Yokota, MD, PhD, FACC, Toyoaki Murohara, MD, PhD, Mitsunori Iwase, MD, PhD, FACC, Akiko Noda, PhD, Sharon A. Hunt, MD, FACC^* and Hannah A. Valantine, MD, MRCP, FACC^*,*

^* Department of Cardiology, Stanford University, Stanford, California, USA
Cardiovascular Division, Department of Clinical Pathophysiology, Nagoya, Japan
Department of Cardiology, Nagoya University, Graduate School of Medicine, Nagoya, Japan
Nagoya University School of Health Sciences, Nagoya, Japan

View larger version (20K): [in a new window]   Figure 1 Relationship between the grade of TxCAD stratified by coronary angiography and plasma HbA1c concentration.

View larger version (22K): [in a new window]   Figure 2 Relationships between percent stenosis determined by coronary angiography and mean intimal thickness (MIT) determined by intracoronary ultrasound (ICUS) (A) and between the severity of transplant coronary artery disease (TxCAD) stratified by coronary angiography and MIT determined by ICUS (B).