The impact of mode of donor brain death on cardiac allograft vasculopathy
An intravascular ultrasound study
Mandeep R. Mehra, MD, FACC*,*,
Patricia A. Uber, pharmD*,
Hector O. Ventura, MD, FACC*,
Robert L. Scott, MD, FACC* and
Myung H. Park, MD*
* Ochsner Cardiomyopathy and Heart Transplantation Center, Ochsner Medical Institutions, New Orleans, Louisiana, USA
View larger version (29K):
[in a new window]
|
Figure 1 Severity of intimal thickening by intravascular ultrasound among cardiac allograft recipients with donors who suffered nonexplosive brain death compared to those with explosive brain death. The explosive brain death donor hearts developed significantly greater intimal thickening, which crossed the prognostically relevant threshold of >0.5 mm.
|
|
View larger version (15K):
[in a new window]
|
Figure 2 Actuarial survival curve depicting freedom from cardiac events during late follow-up demonstrating the adverse impact of explosive brain death on survival compared to non-explosive brain death.
|
|
|
