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Natriuretic peptides as predictors of non-sudden and sudden cardiac death after acute myocardial infarction in the beta-blocking era

Jari M. Tapanainen, MD^*, Kai S. Lindgren, MD^*, Timo H. Mäkikallio, MD^*, Olli Vuolteenaho, MD, Juhani Leppäluoto, MD and Heikki V. Huikuri, MD, FACC^*,*

^* Division of Cardiology, Department of Internal Medicine, Oulu University Hospital, Oulu, Finland
Department of Physiology, Oulu University, Oulu, Finland

View larger version (23K): [in a new window]   Figure 1 Kaplan-Meier survival curves for cardiac mortality of patient groups stratified by the results of natriuretic peptide and ejection fraction (EF) measurements: (A) for atrial natriuretic peptide (ANP), the best cut-off point was at the 60th percentile; (B) for N-terminal atrial natriuretic propeptide (N-ANP), the best cut-off point was at the 85th percentile; (C) for brain natriuretic peptide (BNP), the best cut-off point was at the 60th quartile; (D) for EF, the cut-off point was at the lowest quartile.

View larger version (14K): [in a new window]   Figure 2 Kaplan-Meier survival curves among patients with and without elevated brain natriuretic peptide (BNP).