This Article Abstract Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Cribier, A. Articles by Leon, M. B. Search for Related Content PubMed PubMed Citation Articles by Cribier, A. Articles by Leon, M. B.

Early experience with percutaneous transcatheter implantation of heart valve prosthesis for the treatment of end-stage inoperable patients with calcific aortic stenosis

Alain Cribier, MD, FACC^*,*, Hélène Eltchaninoff, MD^*, Christophe Tron, MD^*, Fabrice Bauer, MD^*, Carla Agatiello, MD^*, Laurent Sebagh, MD^*, Assaf Bash, PhD, Danielle Nusimovici, MD, P. Y. Litzler, MD, Jean-Paul Bessou, MD and Martin B. Leon, MD, FACC

^* Department of Cardiology, Charles Nicolle Hospital, University of Rouen, Rouen, France
Department of Cardiac Surgery, Charles Nicolle Hospital, University of Rouen, Rouen, France
Cardiovascular Research Foundation, Lenox Hill Hospital, New York, New York, USA
Percutaneous Valve Technologies, Fort Lee, New Jersey, USA

View larger version (142K): [in a new window]   Figure 1 Upper view of the percutaneous heart valve, made of three leaflets of equine pericardium inserted within a stainless steel stent.

View larger version (108K): [in a new window]   Figure 2 Sequential steps of implantation. (A) The percutaneous valve in position across the native calcific aortic valve before delivery. GW = extra-stiff guide wire; PM = pacemaker lead in the right ventricle for brief period of rapid pacing at the time of balloon inflation; Sones = Sones catheter advanced over the guide wire from the left femoral artery. (B) Balloon inflation for valve delivery. (C) Post-implantation supra-aortic angiogram showing mild aortic regurgitation. (D) Right anterior oblique-cranial view of the valve showing the circular stent frame pushing away the calcified native valve. Selective left (E) and right (F) coronary angiogram post-implantation showing patent coronary ostia.

View larger version (64K): [in a new window]   Figure 3 Postmortem findings in Patient 3 (upper views). (Left to right) Right coronary (RCA) ostium (arrow); left coronary (LM) ostium (arrow); and free space between the percutaneous valve and the native valve confirming the mechanism of the paravalvular leak (PL).