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Gender differences in ventricular arrhythmia recurrence in patients with coronary artery disease and implantable cardioverter-defibrillators

Rachel Lampert, MD, FACC^*,*, Craig A. McPherson, MD, FACC^*, Jude F. Clancy, MD^*, Teresa L. Caulin-Glaser, MD, FACC, Lynda E. Rosenfeld, MD, FACC^* and William P. Batsford, MD^*

^* Yale University School of Medicine, Department of Internal Medicine, New Haven, Connecticut, USA
McConnell Heart Health Center, Riverside Methodist Hospital, Columbus, Ohio, USA

View larger version (34K): [in a new window]   Figure 1 Incidence of any ventricular tachycardia (VT)/ventricular fibrillation (VF) after implantable cardioverter-defibrillator (ICD) implantation in men versus women, for the entire population and by indication for implantable cardioverter-defibrillator. MADIT = Multicenter Automatic Defibrillator Implantation Trial; MUSTT = Multicenter UnSustained Tachycardia Trial.

View larger version (18K): [in a new window]   Figure 2 Distribution of ventricular arrhythmia frequency by gender. Modified box-plot: thick lines = median, center lines = 75th percentile, and top lines = 90th percentile; whiskers = maximum event frequencies. Event frequency is expressed in percentiles because of skewness of distribution.

View larger version (27K): [in a new window]   Figure 3 Kaplan-Meier survival curve comparing total mortality after implantable cardioverter-defibrillator implantation between men and women.