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High incidence of pacemaker syndrome in patients with sinus node dysfunction treated with ventricular-based pacing in the Mode Selection Trial (MOST)

Mark S. Link, MD^*,*, Anne S. Hellkamp, MS, N. A. Mark Estes, III, MD^*, E. John Orav, PhD, Kenneth A. Ellenbogen, MD, Bassiema Ibrahim, MD^||, Arnold Greenspon, MD^¶, Carlos Rizo-Patron, MD^#, Lee Goldman, MD^**, Kerry L. Lee, PhD, Gervasio A. Lamas, MD MOST Study Investigators

^* Tufts-New England Medical Center, Tufts University School of Medicine, Boston, Massachusetts, USA
Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina, USA
Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA
Medical College of Virginia, Richmond, Virginia, USA
^|| Winthrop University Hospital Cardiology, Mineola, New York, USA
^¶ Jefferson Medical College, Philadelphia, Pennsylvania, USA
^# Cardiology Associates, Lubbock, Texas, USA
^** Department of Medicine, University of California, San Francisco, California, USA
Division of Cardiology, Mount Sinai Medical Center-Miami Heart Institute, Miami Beach, Florida, USA

View larger version (9K): [in a new window]   Figure 1 Kaplan-Meier graph showing the time from implantation to time of permanent crossover for pacemaker syndrome. The y-axis is truncated at 0.7.