Determinants of cardiopulmonary functional improvement after transcatheter atrial septal defect closure in asymptomatic adults
Alessandro Giardini, MD*,*,
Andrea Donti, MD*,
Roberto Formigari, MD, FACC*,
Salvatore Specchia, MD ,
Daniela Prandstraller, MD*,
Gabriele Bronzetti, MD*,
Marco Bonvicini, MD* and
Fernando M. Picchio, MD*
* Pediatric Cardiology and Adult Congenital Unit, Bologna, Italy
Institute of Cardiology, University of Bologna, Bologna, Italy
View larger version (22K):
[in a new window]
|
Figure 1 Peak oxygen uptake (VO2) at baseline and six months after the procedure.
|
|
View larger version (16K):
[in a new window]
|
Figure 2 Correlation between the change in peak oxygen uptake (VO2) and magnitude of pulmonary to systemic flow ratio (Qp/Qs). A significant correlation exists between Qp/Qs magnitude and cardiopulmonary functional improvement after transcatheter atrial septal defect closure.
|
|
View larger version (35K):
[in a new window]
|
Figure 3 Correlation between transthoracic echocardiography and cardiopulmonary testing variables after transcatheter atrial septal defect closure. A significant association exists between postprocedural changes in peak oxygen uptake (VO2) and changes in left ventricular ejection fraction (LVEF) (a) and left ventricular end-diastolic diameter (LVEDD) (b). A similar significant correlation was found between LVEF (c) and LVEDD (d) changes and peak oxygen (O2) pulse variations from baseline.
|
|
View larger version (18K):
[in a new window]
|
Figure 4 Correlation between magnitude of pulmonary to systemic flow ratio (Qp/Qs) and left ventricular ejection fraction (LVEF) improvement after transcatheter atrial septal defect closure.
|
|
|
