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Transesophageal echocardiography improves risk assessment of thrombolysis of prosthetic valve thrombosis: results of the international PRO-TEE registry

Ann T. Tong, MD, FACC^*, Raymond Roudaut, MD, Mehmet Özkan, MD, Alex Sagie, MD, Maie S. A. Shahid, MD^||, Sergio C. Pontes, Jr, MD^¶, Francesc Carreras, MD^#, Steven E. Girard, MD, PhD^**, Samir Arnaout, MD, Raymond F. Stainback, MD, FACC, Ravi Thadhani, MD, MPH, William A. Zoghbi, MD, FACC^*,* Prosthetic Valve Thrombolysis-Role of Transesophageal Echocardiography (PRO-TEE) Registry Investigators

^* Baylor College of Medicine, Houston, Texas, USA
Hopital Cardiologique Du Haut Leveque, Pessac, France
Kosuyolu Heart and Research Hospital, Istanbul, Turkey
Rabin Medical Center, Petah-Tikva, Israel
^|| King Faisel Specialist Hospital and Research Center, Riyadh, Saudi Arabia
^¶ Instituto Dante Pazzanes E. de Cardiologia, San Paulo, Brazil
^# Hospital De La Santa Creu I Sant Pau, Barcelona, Spain
^** Mayo Clinic, Rochester, Minnesota, USA
American University of Beirut, Beirut, Lebanon
Texas Heart Institute, Houston, Texas, USA
Massachusetts General Hospital, Boston, Massachusetts, USA

View larger version (24K): [in a new window]   Figure 1 Relationship of thrombus area by transesophageal echocardiography to overall complication rate and death rate. *p = 0.003; **p < 0.0001 versus thrombus area <0.8 cm2; p = 0.016 and p = 0.07 versus thrombus area <0.8 cm2 and 0.8 to 1.59 cm2, respectively.

View larger version (27K): [in a new window]   Figure 2 Incidence of complication rate and death rate according to the presence or absence of the two risk factors (RF) of thrombus area 0.8 cm2 and previous stroke.

View larger version (20K): [in a new window]   Figure 3 Complication rate and death rate in patients grouped according to New York Heart Association (NYHA) functional class and thrombus size.