Leptin and the ventilatory response to exercise in heart failure
Robert Wolk, MD, PhD*,
Bruce D. Johnson, PhD* and
Virend K. Somers, MD, PhD, FACC*,*
* Mayo Clinic, Rochester, Minnesota, USA
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Figure 1 Relationship between VE/VCO2 slope and nonadjusted leptin levels (a) and body fat (b) divided into tertiles (analysis of variance [ANOVA], followed by Newman-Keuls multiple comparison post-hoc tests). Data are expressed as mean ± SEM. When leptin levels adjusted for body fat were divided into tertiles, the relationship between the adjusted leptin tertiles and VE/VCO2 slope was virtually identical to that between VE/VCO2 slope and unadjusted leptin. VCO2 = carbon dioxide production; VE = ventilation per unit time.
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