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J Am Coll Cardiol, 2003; 42:1446-1453, doi:10.1016/S0735-1097(03)01057-X
© 2003 by the American College of Cardiology Foundation
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Predictors of late development of heart failure in stable survivors of myocardial infarction

The CARE study

Eldrin F. Lewis, MD, MPH*, Lemuel A. Moye, MD, PhD{dagger}, Jean L. Rouleau, MD, FACC{ddagger}, Frank M. Sacks, MD*, J. Malcolm O. Arnold, MD, FACC§, J. Wayne Warnica, MD, FACC||, Greg C. Flaker, MD, FACC, Eugene Braunwald, MD, FACC* and Marc A. Pfeffer, MD, PhD, FACC*,*

* Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA
{dagger} University of Texas School of Public Health, Houston, Texas, USA
{ddagger} University of Toronto, Toronto, Ontario, Canada
§ London Health Sciences Center, London, Ontario, Canada
|| Foothills Hospital, Calgary, Alberta, Canada
University of Missouri Hospital and Clinics, Columbia, Missouri, USA



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Figure 1 Cumulative incidence of hospitalization for heart failure (HF) and death or hospitalization for HF in patients enrolled in the CARE trial without a previous history of HF. The upper line represents the cumulative incidence of all-cause mortality or hospitalization for HF, and the lower line represents only HF hospitalizations.

 


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Figure 2 The impact of age on the development of heart failure after an myocardial infarction in the CARE trial.

 


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Figure 3 The impact of baseline left ventricular ejection fraction (LVEF) on the development of heart failure after an myocardial infarction in the CARE trial.

 


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Figure 4 (A) The overall effect of the combination of age and left ventricular ejection fraction (LVEF) on the rate of hospitalizations for heart failure (HF) over a mean follow-up of five years in the CARE population. (B) The overall effect of the combination of age and LVEF on the rate of hospitalizations for HF and death over a mean follow-up of five years in the CARE population.

 




 
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