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A randomized trial of polytetrafluoroethylene-membrane-covered stents compared with conventional stents in aortocoronary saphenous vein grafts

Volker Schächinger, MD^*,*, Christian W. Hamm, MD, FACC, Thomas Münzel, MD, Michael Haude, MD, Stephan Baldus, MD, Eberhard Grube, MD, FACC^||, Tassilo Bonzel, MD^¶, Thomas Konorza, MD, Ralf Köster, MD, Roman Arnold, MD, Jürgen Haase, MD^#, Peter Probst, MD, FACC^**, Jürgen vom Dahl, MD, Franz-Josef Neumann, MD, Harald Mudra, MD, Benno Hennen, MD^||||, Ludger Thiele^¶¶, Andreas M. Zeiher, MD^* STING (STents IN Grafts) Investigators

^* J. W. Goethe Universität, Frankfurt/Main, Germany
Kerckhoffklinik Bad Nauheim, Bad Nauheim, Germany
Universitätsklinik Eppendorf, Hamburg, Germany
Universitätsklinikum Essen, Essen, Germany
^|| Krankenhaus Siegburg, Siegburg, Germany
^¶ Städtisches Klinikum Fulda, Fulda, Germany
^# Rotes-Kreuz Krankenhaus Frankfurt/Main, Frankfurt/Main, Germany
^** Allgemeines Krankenhaus Wien, Wien, Austria
Klinikum d. Rhein. Westf. TH Aachen, Aachen, Germany
Deutsches Herzzentrum München, München, Germany
Krankenhaus München Neuperlach, München, Germany
^|||| Universitätskliniken des Saarlandes, Homburg/Saar, Germany
^¶¶ Jomed GmbH, Rangendingen, Germany

View larger version (27K): [in a new window]   Figure 1 Trial profile. *Index angiogram was not suitable for quantitative analysis in one patient. Angio = coronary angiogram; pt. = patient.

View larger version (22K): [in a new window]   Figure 2 Cumulative distribution of minimal luminal diameter (MLD) assessed by quantitative coronary angiography. (A) Patients intended to treat: MLD before intervention and after intervention. (B) Patients undergoing follow-up angiography: MLD after intervention and at follow-up. Diamond = Stentgraft; circle = Flex; dotted = after intervention.

View larger version (28K): [in a new window]   Figure 3 Kaplan-Meier analyses of cumulative event rates. (A) Cumulative event rate of secondary end point: death, myocardial infarction (MI), or target lesion revascularization (TLR). (B) Cumulative event rate: death or MI. (C) Cumulative event rate: TLR.