Thoracoscopic extracardiac obliteration of the left atrial appendage for stroke risk reduction in atrial fibrillation
Joseph L. Blackshear, MD*,*,
W. Dudley Johnson, MD ,
John A. Odell, MD*,
Vickie S. Baker, RN*,
Mary Howard, RN ,
Lesly Pearce, MS ,
Christopher Stone, MD ,
Douglas L. Packer, MD and
Hartzell V. Schaff, MD
* Mayo Clinic Jacksonville, Jacksonville, Florida, USA
W. Dudley Johnson Heart Care Center, Milwaukee, Wisconsin, USA
Biostatistical Consultant, Minot, North Dakota, USA
Mayo Clinic, Rochester, Minnesota, USA

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Figure 1 Intraoperative transesophageal echocardiographic images of the left atrial appendage before (left) and after (right) LAPTONI.
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Figure 2 Cumulative proportion of 15 patients with atrial fibrillation (AF) after surgical left atrial appendage obliteration (LAPTONI) without thromboembolism (straight line). The reference lines are based on thromboembolism rates for non-anticoagulated AF patients aged 65 to 75 years in the Atrial Fibrillation Investigators' (AFI) meta-analysis with at least one risk factor (upper dashed line) (1) and for non-anticoagulated AF patients of any age with a history of prior thromboembolism in AFI and the European Atrial Fibrillation Trial (EAFT) (bottom dashed line) (1,2).
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