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Prognostic significance of impairment of heart rate response to exercise

Impact of left ventricular function and myocardial ischemia

Abdou Elhendy, MD, PhD^*, Douglas W. Mahoney, MSc, Bijoy K. Khandheria, MD, FACC^*, Kelli Burger, BSc and Patricia A. Pellikka, MD, FACC^*,*

^* Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA
Department of Biostatistics, Mayo Clinic, Rochester, Minnesota, USA

View larger version (33K): [in a new window]   Figure 1 Kaplan-Meier survival curves in patients who did and did not reach 85% of the target heart rate (HR), with a normal and an abnormal exercise echocardiogram. (A) Hard cardiac events. (B) All-cause mortality. MI = myocardial infarction.

View larger version (30K): [in a new window]   Figure 2 Kaplan-Meier survival curves in patients with and without chronotropic index <0.8, with a normal and an abnormal exercise echocardiogram. (A) Hard cardiac events. (B) All-cause mortality. MI = myocardial infarction.