Prognostic significance of impairment of heart rate response to exercise
Impact of left ventricular function and myocardial ischemia
Abdou Elhendy, MD, PhD*,
Douglas W. Mahoney, MSc ,
Bijoy K. Khandheria, MD, FACC*,
Kelli Burger, BSc and
Patricia A. Pellikka, MD, FACC*,*
* Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA
Department of Biostatistics, Mayo Clinic, Rochester, Minnesota, USA

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Figure 1 Kaplan-Meier survival curves in patients who did and did not reach 85% of the target heart rate (HR), with a normal and an abnormal exercise echocardiogram. (A) Hard cardiac events. (B) All-cause mortality. MI = myocardial infarction.
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Figure 2 Kaplan-Meier survival curves in patients with and without chronotropic index <0.8, with a normal and an abnormal exercise echocardiogram. (A) Hard cardiac events. (B) All-cause mortality. MI = myocardial infarction.
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