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Prediction of sudden cardiac death after myocardial infarction in the beta-blocking era

Heikki V. Huikuri, MD, FACC^*,*, Jari M. Tapanainen, MD^*, Kai Lindgren, MD^*, Pekka Raatikainen, MD^*, Timo H. Mäkikallio, MD^*, K. E. Juhani Airaksinen, MD^* and Robert J. Myerburg, MD, FACC

^* Division of Cardiology, Department of Medicine, University of Oulu, Oulu, Finland
Division of Cardiology, University of Miami, Miami, Florida, USA

View larger version (17K): [in a new window]   Figure 1 Cumulative event rates for total mortality and cardiac mortality (left panel) and non-sudden cardiac death (SCD) and SCD mortality (right panel). The proportion of patients who died nonsuddenly was higher than that of the patients who died suddenly, particularly during the first 18 months after acute myocardial infarction.

View larger version (31K): [in a new window]   Figure 2 Mean (±SD) ejection fraction (upper left panel), standard deviation of N-N intervals (SDNN) measured from 24-h Holter recordings (upper right panel), QT dispersion (lower left panel), and QRS duration (lower right panel) measured by signal-averaged electrocardiogram (SAECG) among the survivors and those who experienced a non-sudden cardiac death (SCD) or SCD during follow-up. All variables differed significantly between survivors and those who had a non-SCD, although none of these variables differed between the survivors and those who experienced SCD.