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J Am Coll Cardiol, 2003; 42:593-599, doi:10.1016/S0735-1097(03)00786-1
© 2003 by the American College of Cardiology Foundation
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Is aortic stenosis a preventable disease?

Kwan-Leung Chan, MD, FRCPC, FACC*,*

* Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada



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  		Figure 1 Pathogenetic mechanisms in aortic valve stenosis. Lipoproteins are involved in multiple pathways, which lead to fibrosis and calcification. From O'Brien et al. (20), Arterioscler Thromb Vasc Biol 1996, reprinted with permission. LDL = low-density lipoprotein.

 




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