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J Am Coll Cardiol, 2003; 42:219-225, doi:10.1016/S0735-1097(03)00624-7
© 2003 by the American College of Cardiology Foundation
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Determinants of target vessel failure in chronic total coronary occlusions after stent implantation

The influence of collateral function and coronary hemodynamics

Gerald S. Werner, MD, FACC*,*, Philipp Bahrmann, MD*, Oliver Mutschke, MD*, Ulf Emig, MD*, Stefan Betge, MD*, Markus Ferrari, MD* and Hans R. Figulla, MD*

* Clinic for Internal Medicine III, Friedrich-Schiller-University, Jena, Germany



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  		Figure 1 Difference in stent length among patients with and without target vessel failure (TVF) after recanalization of a chronic total coronary occlusion. Individual data points and mean ± SD are shown. The p values represent the post-hoc analysis of the analysis of variance (p = 0.006).

 


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  		Figure 2 The difference in recurrence rate after recanalization of chronic total coronary occlusions depending on the number of implanted stents. The relative distribution is shown; the numbers indicate the absolute number of patients. Chi-squared test for the difference between groups: p = 0.037. TVF= target vessel failure.

 


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  		Figure 3 Collateral pressure index before (baseline) (A) and after (recruitable) (B) recanalization of a chronic total coronary occlusion with no significant difference between groups. Individual data points and mean ± SD. ANOVA = analysis of variance; TVF = target vessel failure.

 


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  		Figure 4 Coronary flow velocity reserve (CFVR) (A) and fractional flow reserve (FFR) (B) among patients with and without target vessel failure (TVF) after recanalization of a chronic total coronary occlusion. Individual data points and mean ± SD are shown. The p values represent the analysis of variance (ANOVA) result for CFVR and the post-hoc analysis of the ANOVA for FFR (p = 0.027).

 


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  		Figure 5 Global (A) and regional (B) left ventricular (LV) function before recanalization and at follow-up in patients with and without target vessel failure (TVF). There were no differences at baseline, with improvement during follow-up in all patients except those with reocclusion. p values for paired t test. Open bars = baseline; hatched bars = follow-up.

 




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Copyright © 2003 by the American College of Cardiology Foundation.