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J Am Coll Cardiol, 2003; 42:1933-1940, doi:10.1016/j.jacc.2003.07.016
© 2003 by the American College of Cardiology Foundation
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The relationship between cholesterol and survival in patients with chronic heart failure

Mathias Rauchhaus, MD*{dagger}, Andrew L. Clark, MD{ddagger},*, Wolfram Doehner, MD*, Constantinos Davos, MD, PhD*, Aidan Bolger, BSc*, Rakesh Sharma, BSc*, Andrew J. S. Coats, DM* and Stefan D. Anker, MD, PhD*§

* Clinical Cardiology, National Heart and Lung Institute, Imperial College School of Medicine, London, United Kingdom
{dagger} Klinik und Poliklinik für Innere Medizin III, Martin-Luther-Universität, Halle, Germany
{ddagger} Academic Cardiology, Castle Hill Hospital, Hull, United Kingdom
§ Franz-Volhard-Klinik (Charité, Campus Berlin-Buch) am Max-Delbrück Centrum für Molekulare Medizin, Berlin, Germany



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Figure 1 Survival in the derivation study with patients classified into quartiles of total cholesterol (quartile 1 being the lowest; 4 the highest). Log-rank p = 0.0016 for the differences between quartiles.

 


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Figure 2 Survival in the validation study related to the best predictive value for serum cholesterol found in the derivation study. Log-rank p = 0.0011 for the difference between groups.

 


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Figure 3 Survival by etiology and cholesterol in the validation study. Log-rank p = 0.05 for comparison between high and low cholesterol in nonischemic etiology and p = 0.001 for ischemic etiology.

 





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