Transient ischemic dilation ratio of the left ventricle is a significant predictor of future cardiac events in patients with otherwise normal myocardial perfusion SPECT
Aiden Abidov, MD, PhD*,
Jeroen J. Bax, MD ,
Sean W. Hayes, MD*,
Rory Hachamovitch, MD, MSc, FACC ,
Ishac Cohen, PhD*,
James Gerlach, CNMT*,
Xingping Kang, MD*,
John D. Friedman, MD, FACC*,
Guido Germano, PhD, FACC* and
Daniel S. Berman, MD, FACC*,*
* Department of Imaging (Division of Nuclear Medicine) and Department of Medicine (Division of Cardiology), Cedars-Sinai Medical Center, Los Angeles, California, USA
Leiden University Medical Center, Leiden, The Netherlands
Keck School of Medicine, University of Southern California, Los Angeles, California, USA
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Figure 1 Annual rates of first future cardiac events (total events) and hard events in patients with normal myocardial perfusion single photon emission computed tomography distributed by quartiles of transient ischemic dilation (TID) ratio. *p < 0.001 across the groups; p = 0.006 for highest quartile versus all others. Open bars = total events; solid bars = hard events.
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Figure 2 Annual total event rate as a function of stress type and presence of highest transient ischemic dilation (TID) quartile; controls are patients in three lower quartiles of TID. Open bars = controls; solid bars = highest quartile of TID.
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Figure 3 Incremental value of the presence of highest transient ischemic dilation (TID) quartile in prediction of total events in patients with normal myocardial perfusion single photon emission computed tomography.
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