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Assessment of coronary flowreserve by coronary pressure measurement

Comparison with flow- or Velocity-Derived coronary flow reserve

Takashi Akasaka, MD^*,*, Atsushi Yamamuro, MD, Norio Kamiyama, MD^*, Yuji Koyama, MD^*, Maki Akiyama, MD^*, Nozomi Watanabe, MD^*, Yoji Neishi, MD^*, Tsutomu Takagi, MD, Evgeny Shalman, PhD, Chen Barak, PhD and Kiyoshi Yoshida, MD, FACC^*

^* Department of Cardiology, Kawasaki Medical School, Kurashiki City, Okayama, Japan
Department of Cardiology, Kobe General Hospital, Chuo-ku, Kobe, Japan
Florence Medical Ltd., Sharona Center, Kfar-Saba, Israel

View larger version (25K): [in a new window]   Figure 1 Scatterplots of pressure-derived coronary flow reserve (CFR) on the y-axis and flow-derived CFR on the x-axis (top) and of the difference between pressure- and flow-derived CFR on the y-axis and the mean value of the two on the x-axis (bottom) in an animal experimental study.

View larger version (20K): [in a new window]   Figure 2 Scatterplot of the difference between pressure- and flow-derived coronary flow reserve on the y-axis and fractional flow reserve on the x-axis in an animal experimental study.

View larger version (24K): [in a new window]   Figure 3 Scatterplots of pressure-derived coronary flow reserve (CFR) on the y-axis and velocity-derived CFR on the x-axis (top) and of the difference between pressure- and velocity-derived CFR on the y-axis and the mean value of the two on the x-axis (bottom) in a human study.

View larger version (20K): [in a new window]   Figure 4 Scatterplot of the difference between pressure- and velocity-derived coronary flow reserve (CFR) on the y-axis and fractional flow reserve on the x-axis in a human study.