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The metabolic syndrome, diabetes, and subclinicalatherosclerosis assessed by coronary calcium

Nathan D. Wong, PhD, FACC, Maria G. Sciammarella, MD^*, Donna Polk, MD, MPH^*, Amy Gallagher, MPH^*, Lisa Miranda-Peats, MPH^*, Brian Whitcomb, BS^*, Rory Hachamovitch, MD, FACC^*, John D. Friedman, MD, FACC^*, Sean Hayes, MD^* and Daniel S. Berman, MD, FACC^*,*

^* Departments of Imaging and Medicine, Cedars-Sinai Medical Center, Los Angeles, USA
Heart Disease Prevention Program, University of California, Irvine, California, USA

View larger version (38K): [in a new window]   Figure 1 Prevalence of coronary artery calcium (CAC) by disease category and gender. Gray bars = neither condition; striped bars = metabolic syndrome (MetS); black bars = diabetes. p = 0.0002 for men and p = 0.02 for women for any CAC and p = 0.01 for men and p = 0.19 for women for CAC 75th percentile across groups (MetS, diabetes, and neither condition).

View larger version (35K): [in a new window]   Figure 2 Prevalence of coronary artery calcium (CAC) and significant CAC (75th percentile) by number of metabolic syndrome risk factors. Striped bars = present; black bars = CAC 75th percentile. p < 0.0001 for CAC present and p = 0.0002 for CAC 75th percentile for test of trend across number of metabolic risk factors for CAC present and for CAC 75th percentile.

View larger version (20K): [in a new window]   Figure 3 Proportion of persons identified with the metabolic syndrome classified by presence of >20% 10-year estimated risk of coronary heart disease (CHD) and significant coronary artery calcium (CAC) (75th percentile). Striped bar = CAC 75th percentile; gray bar = 10-year CHD risk >20%; black bar = either or both.