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J Am Coll Cardiol, 2003; 41:1523-1528, doi:10.1016/S0735-1097(03)00257-2
© 2003 by the American College of Cardiology Foundation
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Cardiac resynchronization therapyhomogenizes myocardial glucosemetabolism and perfusion in dilatedcardiomyopathy and left bundle branch block

Bernd Nowak, MD*,*, Anil M. Sinha, MD, PhD{dagger}, Wolfgang M. Schaefer, MD, PhD*, Karl-Christian Koch, MD{dagger}, Hans-Juergen Kaiser, PhD*, Peter Hanrath, MD, FACC{dagger}, Udalrich Buell, MD* and Christoph Stellbrink, MD{dagger}

* Department ofNuclear Medicine, University Hospital, Aachen University of Technology, Aachen, Germany
{dagger} Internal Medicine I (Cardiology), University Hospital, Aachen University of Technology, Aachen, Germany



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  		Figure 1 Example of 18F-fluorodeoxyglucose-positron emission tomography and technetium-99m-sestamibi single-photon emission computed tomography images at baseline and during cardiac resynchronization therapy in a 50-year-old female patient with severe left ventricular dilation due to nonischemic cardiomyopathy. Shown are representative short-axis and horizontal long-axis slices of 1.2 cm thickness, as well as individual uptake values of the respective wall areas. A = anterior wall area; L = lateral wall area; P = posterior wall area; S = septal wall area.

 


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  		Figure 2 Mean (±SD) relative 18F-fluorodeoxyglucose (FDG) (A) and technetium-99m-sestamibi (B) uptake values of the four left ventricular wall areas, as well as septal-to-lateral ratios at baseline and during cardiac resynchronization therapy (CRT) in 15 patients. *p < 0.05, {dagger}p < 0.01, and {ddagger}p < 0.001 compared with FDG.

 




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