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Role of chronic hyperglycemia in the pathogenesis of coronary microvascular dysfunction in diabetes

Marcelo F. Di Carli, MD^*,*, James Janisse, PhD, George Grunberger, MD^* and Joel Ager, PhD

^* Department of Medicine, Wayne State University School of Medicine, Detroit, Michigan, USA
Department of Radiology, Wayne State University School of Medicine, Detroit, Michigan, USA
Center for Healthcare Effectiveness Research, Wayne State University School of Medicine, Detroit, Michigan, USA
Positron Emission Tomography Center , Children’s Hospital of Michigan, Detroit, Michigan, USA

View larger version (18K): [in a new window]   Figure 1 Percent change in myocardial blood flow in response to the infusion of adenosine and the cold pressor test in the subjects with type 1 and type 2 diabetes and in the healthy controls. All p values are based on Tukey post-hoc tests.