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Hypertrophic cardiomyopathy in a large community-based population: clinical outcome and identification of risk factors for sudden cardiac death and clinical deterioration

Marcel J. M. Kofflard, MD, Folkert J. Ten Cate, MD, FACC^*,*, Chris van der Lee, MD^* and Ron T. van Domburg, MSc^*

^* Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands
Albert Schweitzer Hospital Department of Cardiology, Dordrecht, The Netherlands

View larger version (12K): [in a new window]   Figure 1 Kaplan-Meier survival curve of 225 patients with hypertrophic cardiomyopathy (HC) and age-matched controls. Numbers above horizontal axis refer to numbers of patients at each follow-up period.

View larger version (26K): [in a new window]   Figure 2 Chart showing New York Heart Association (NYHA) functional classification in patients with a left ventricular outflow tract gradient 50 mm Hg at rest or provocation. The total number of patients with obstructive hypertrophic cardiomyopathy is expressed in bold (n = 98). The patients treated by surgical therapy are expressed in italics (n = 57). The first column represents the NYHA functional class of the patients at presentation to our institution. The second column represents the NYHA functional class of nonoperated patients at their latest visit or the NYHA functional class of patients treated by surgery just before operation. The third column represents the NYHA functional class of patients treated by surgery at their latest visit.

View larger version (16K): [in a new window]   Figure 3 Chart showing New York Heart Association (NYHA) functional classification in 127 patients without a left ventricular outflow tract gradient. The first column represents the NYHA functional class of the patients at presentation to our institution. The second column represents the NYHA functional class of the patients at their latest visit.