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Angiotensin-converting enzyme gene polymorphism interacts with left ventricular ejection fraction and brain natriuretic peptide levels to predict mortality after myocardial infarction

^* Christchurch Cardioendocrine Research Group, Department of Medicine, Christchurch School of Medicine and Health Sciences, Christchurch, New Zealand

View larger version (19K): [in a new window]   Figure 1 Kaplan-Meier survival curves for the three angiotensin-converting enzyme genotype groups. Solid line = DD genotype; dotted line = ID genotype; dashed line = II genotype.

View larger version (22K): [in a new window]   Figure 2 Kaplan-Meier survival curves illustrating the interaction between angiotensin-converting enzyme genotype (ID/DD vs. II) and (a) left ventricular ejection fraction (LVEF) and (b) brain natriuretic peptide (BNP) below or above overall median values. Medians: LVEF, 48%; BNP, 22 pmol/l. *p < 0.05; **p < 0.01; p < 0.001.