Angiotensin-converting enzyme gene polymorphism interacts with left ventricular ejection fraction and brain natriuretic peptide levels to predict mortality after myocardial infarction
Barry R. Palmer, PhD*,
Anna P. Pilbrow, BSc (Hons)*,
Tim G. Yandle, PhD*,
Chris M. Frampton, PhD*,
A. Mark Richards, MD*,
M. Gary Nicholls, MD, FACC* and
Vicky A. Cameron, PhD*,*
* Christchurch Cardioendocrine Research Group, Department of Medicine, Christchurch School of Medicine and Health Sciences, Christchurch, New Zealand

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Figure 1 Kaplan-Meier survival curves for the three angiotensin-converting enzyme genotype groups. Solid line = DD genotype; dotted line = ID genotype; dashed line = II genotype.
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Figure 2 Kaplan-Meier survival curves illustrating the interaction between angiotensin-converting enzyme genotype (ID/DD vs. II) and (a) left ventricular ejection fraction (LVEF) and (b) brain natriuretic peptide (BNP) below or above overall median values. Medians: LVEF, 48%; BNP, 22 pmol/l. *p < 0.05; **p < 0.01; p < 0.001.
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