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J Am Coll Cardiol, 2003; 41:729-736, doi:10.1016/S0735-1097(02)02927-3
© 2003 by the American College of Cardiology Foundation
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Angiotensin-converting enzyme gene polymorphism interacts with left ventricular ejection fraction and brain natriuretic peptide levels to predict mortality after myocardial infarction

Barry R. Palmer, PhD*, Anna P. Pilbrow, BSc (Hons)*, Tim G. Yandle, PhD*, Chris M. Frampton, PhD*, A. Mark Richards, MD*, M. Gary Nicholls, MD, FACC* and Vicky A. Cameron, PhD*,*

* Christchurch Cardioendocrine Research Group, Department of Medicine, Christchurch School of Medicine and Health Sciences, Christchurch, New Zealand



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  		Figure 1 Kaplan-Meier survival curves for the three angiotensin-converting enzyme genotype groups. Solid line = DD genotype; dotted line = ID genotype; dashed line = II genotype.

 


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  		Figure 2 Kaplan-Meier survival curves illustrating the interaction between angiotensin-converting enzyme genotype (ID/DD vs. II) and (a) left ventricular ejection fraction (LVEF) and (b) brain natriuretic peptide (BNP) below or above overall median values. Medians: LVEF, 48%; BNP, 22 pmol/l. *p < 0.05; **p < 0.01; {dagger}p < 0.001.

 




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