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Atriobiventricular pacing improves exercise capacity in patients with heart failure and intraventricular conduction delay

Chetan Varma, MD^*, Sanjay Sharma, MD^*, Sam Firoozi, MD^*, William J. McKenna, MD, FACC^*,*, Jean-Claude Daubert, MD, FACC Multisite Stimulation in Cardiomyopathy (MUSTIC) Study Group

^* Department of Cardiological Sciences, St. Georges Hospital Medical School, London, United Kingdom
Département de Cardiologie & Maladies Vasculaires, Centre Cardio-Pneumologique, Hôpital Pontchaillou, Rennes, France

View larger version (72K): [in a new window]   Figure 1 Comparison of measures of submaximal exercise during active and inactive pacing. Significant increases were observed in the distance walked in 6 min (meters, p = 0.001) and anaerobic threshold (AT, ml/kg/min, p = 0.02) during active pacing. A significant improvement was observed in the minute ventilation/ventilated carbon dioxide (VE/VCO2, p = 0.03). Black bars= randomization; vertically lined bar = inactive pacing; horizontally lined bar = active pacing.