HOME SUBSCRIPTIONS CURRENT ISSUE PAST ISSUES CARDIOSOURCE SEARCH HELP FEEDBACK		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Abstract Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Kasama, S. Articles by Kurabayashi, M. Search for Related Content PubMed PubMed Citation Articles by Kasama, S. Articles by Kurabayashi, M.

Effect of spironolactone on cardiacsympathetic nerve activity and left ventricular remodeling in patients with dilated cardiomyopathy

Shu Kasama, MD^*,*, Takuji Toyama, MD^*, Hisao Kumakura, MD, Yoshiaki Takayama, MD, Shuichi Ichikawa, MD, Tadashi Suzuki, MD^* and Masahiko Kurabayashi, MD^*

^* Second Department of Internal Medicine, Gunma University School of Medicine, MaebashiJapan
Kitakanto Cardiovascular Hospital, Gunma, Japan

View larger version (15K): [in a new window]   Figure 1 Cardiac 123I-MIBG uptake was quantified as the H/M ratio 4 h after injection, using regions of interest positioned over the heart (H) and upper mediastinum (M).

View larger version (14K): [in a new window]   Figure 2 Segmentation scheme used to quantitate regional 123I-MIBG uptake.

View larger version (18K): [in a new window]   Figure 3 Changes in New York Heart Association (NYHA) functional class during treatment in the two groups.

View larger version (13K): [in a new window]   Figure 4 Correlation between the changes in the 123I-MIBG scintigraphic findings and changes in left ventricular end-diastolic volume (LVEDV) after six months of spironolactone treatment in 15 patients with dilated cardiomyopathy. Delta LVEDV = LVEDV value after six months – pretreatment value of LVEDV; delta TDS = total defect score (TDS) value after six months – pretreatment value of TDS; delta H/M ratio = H/M ratio after six months – pretreatment value of H/M ratio; delta WR = washout rate (WR) value after six months – pretreatment value of WR.