Long-term follow-up of coronary artery disease presenting in young adults
Jason H. Cole, MD*,
Joseph I. Miller, III, MD*,*,
Laurence S. Sperling, MD* and
William S. Weintraub, MD, FACC*
* Emory Center for Outcomes Research and Section of Preventive Cardiology, Division of Cardiology, Emory University School of Medicine, Atlanta, Georgia, USA
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Figure 1 Survival in diabetic and nondiabetic patients. The increase in diabetic mortality starts in the first year after angiography and continues over the 15 years of follow-up (p < 0.0001). After 15 years only 35% of the diabetic patients had survived.
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Figure 2 Survival for patients with a prior myocardial infarction (MI) versus no prior MI. A significant increase in mortality is seen starting after the second year for the individuals with a prior MI, and they had 45% mortality at 15 years (p < 0.0001).
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Figure 3 Fifteen-year survival for patients categorized by ejection fractions (EFs) <30%, 30%–49%, and >50%. Patients with an EF <30% had a dramatic mortality increase during the first year of follow-up, and only 17% were alive at 15 years (p < 0.0001 for differences across the three groups of therapy).
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Figure 4 Freedom from myocardial infarction (MI) based on initial therapy. The coronary bypass patients had the highest rates of MI starting around year 8, reflecting the time of expected vein graft loss (p = 0.04 for differences in survival across three initial therapy groups).
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