JACC
HOME SUBSCRIPTIONS CURRENT ISSUE PAST ISSUES CARDIOSOURCE SEARCH HELP FEEDBACK
QUICK SEARCH:   [advanced]


     

J Am Coll Cardiol, 2003; 41:426-432, doi:10.1016/S0735-1097(02)02822-X
© 2003 by the American College of Cardiology Foundation
This Article
Right arrow Abstract Freely available
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Braith, R. W.
Right arrow Articles by Wood, C. E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Braith, R. W.
Right arrow Articles by Wood, C. E.

High-dose angiotensin-converting enzyme inhibition restores body fluid homeostasis in heart-transplant recipients

Randy W. Braith, PhD*,*, Roger M. Mills, MD, FACC*, Christopher S. Wilcox, MD, PhD{dagger}, Gary L. Davis, MD*, James A. Hill, MD, FACC* and Charles E. Wood, PhD*

* Center for Exercise Science, College of Health and Human Performance, and the Departments of Medicine and Physiology, University of Florida, Gainesville, Florida, USA
{dagger} Department of Medicine, Georgetown University, Washington, DC, USA



View larger version (32K):

[in a new window]
  		Figure 1 Changes ({delta}) in blood pressure during a 4-h infusion of isotonic saline and the 48-h period after the infusion in heart- (HTR) and liver- transplant recipients (LTR) both before (W/O ACEi) and after stabilization (With ACEi) on captopril (225 mg/day). Data are mean value ± SEM. *p ≤ 0.05 versus baseline value. {dagger}p ≤ 0.05 HTRs before captopril versus HTRs after captopril and LTR both before and after captopril. ACEi = angiotensin-converting enzyme inhibition.

 


View larger version (27K):

[in a new window]
  		Figure 2 Changes in urine flow rate (UV) and urinary salt excretion (UnaV) during a 4-h infusion of isotonic saline and the 48-h period after the infusion in heart- (HTR) and liver-transplant recipients (LTR) both before (W/O ACEi) and after stabilization (With ACEi) on captopril (225 mg/day). Data are mean value ± SEM. *p ≤ 0.05 HTRs before captopril versus HTRs after captopril and LTR both before and after captopril. ACEi = angiotensin-converting enzyme inhibition.

 


View larger version (25K):

[in a new window]
  		Figure 3 Changes ({delta}) in plasma angiotensin II (ANG II) and aldosterone (ALDO) concentrations during a 4-h infusion of isotonic saline and the 48-h period after the infusion in heart- (HTR W/O ACEi) and liver- transplant recipients (LTR W/O ACEi) before stabilization on captopril (225 mg/day). Data are mean value ± SEM. *p ≤ 0.05 versus baseline value. ACEi = angiotensin-converting enzyme inhibition.

 


View larger version (34K):

[in a new window]
  		Figure 4 Changes ({delta}) in plasma arginine vasopressin (AVP) and atrial natriuretic peptide (ANP) concentrations during a 4-h infusion of isotonic saline and the 48-h period after the infusion in heart- (HTR) and liver- transplant recipients (LTR) both before (W/O ACEi) and after stabilization (With ACEi) on captopril (225 mg/day). Data are mean value ± SEM. *p ≤ 0.05 versus baseline value. {dagger}p ≤ 0.05 HTRs versus LTR both before and after captopril. ACEi = angiotensin-converting enzyme inhibition.

 




HOME SUBSCRIPTIONS CURRENT ISSUE PAST ISSUES CARDIOSOURCE SEARCH HELP FEEDBACK
Copyright © 2003 by the American College of Cardiology Foundation.