Severe renal dysfunction complicating cardiogenic shock is not a contraindication to mechanical support as a bridge to cardiac transplantation
Umesh N. Khot, MD*,*,
Micky Mishra, MD ,
M. Hilal Yamani, MD*,
Nicholas G. Smedira, MD, FACC ,
Emil Paganini, MD ,
Mike Yeager, RN ,
Tiffany Buda, RN ,
Patrick M. McCarthy, MD ,
James B. Young, MD, FACC* and
Randall C. Starling, MD, MPH, FACC*
* Department of Cardiovascular Medicine, Kaufman Center for Heart Failure, , Cleveland, Ohio, USA
Department of Internal Medicine, Cleveland, Ohio, USA
Department of Nephrology and Hypertension, Cleveland, Ohio, USA
Department of Cardiothoracic Surgery, The Cleveland Clinic Foundation, Cleveland, Ohio, USA

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Figure 1 Change in serum creatinine with ventricular assist device (VAD) placement in VAD patients who died early (<1 month), late (>1 month), and those who survived to cardiac transplantation. The three patients who died early were on continuous venovenous hemodialysis at the time of death. TX = transplantation.
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Figure 2 Comparison of 30-day survival, 6-month survival, and survival to cardiac transplantation in ventricular assist device patients according to the absence or presence of severe renal failure (RF).
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Figure 3 Comparison of 30-day, 6-month, and one-year survival post-transplantation in ventricular assist device patients who survived to cardiac transplantation according to the absence or presence of severe renal failure (RF). TX = Transplantation.
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