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Common genetic variation of the cholesteryl ester transfer protein gene strongly predicts future cardiovascular death in patients with coronary artery disease

Stefan Blankenberg, MD^*,*, Hans J. Rupprecht, MD^*, Christoph Bickel, MD^*, Xian-Cheng Jiang, PhD, Odette Poirier, PhD, Karl J. Lackner, MD, J.ürgen Meyer, MD, FACC^*, François Cambien, MD, Laurence Tiret, PhD AtheroGene Investigators

^* Department of Medicine II, Johannes Gutenberg-University Mainz, Mainz, Germany
Department of Clinical Chemistry, Johannes Gutenberg-University Mainz, Mainz, Germany
Institut National de la Santé et de la Recherche Médicale (INSERM) U525, Faculté de Médecine Pitié-Salpêtrière, Paris, France
Department of Anatomy and Cell Biology, State University of New York, Downstate Medical Center, Brooklyn, New York, USA

View larger version (18K): [in a new window]   Figure 1 Kaplan-Meier survival plots for cardiovascular mortality according to the cholesteryl ester transfer protein (CETP) polymorphisms.

View larger version (20K): [in a new window]   Figure 2 Hazard risk ratios of future cardiovascular death according to the cholesteryl ester transfer protein (CETP)/C-629A polymorphism and statin therapy.