The effect of atrial pacing therapies on atrial tachyarrhythmia burden and frequency
Results of a randomized trial in patients with bradycardia and atrial tachyarrhythmias
Michael A. Lee, MD, FACC*,*,
Richard Weachter, MD, FACC
,
Scott Pollak, MD, FACC
,
Mark S. Kremers, MD, FACC
,
Ajay M. Naik, MD||,
Russell Silverman, MD, FACC¶,
Joann Tuzi, RN**,
Wayne Wang, MS**,
Linda J. Johnson, PhD**,
David E. Euler, PhD** ATTEST Investigators
* John Muir/Mount Diablo Medical Center, Walnut Creek, California, USA
Ferrell-Duncan Clinic and Cox Medical Center, Springfield, Missouri, USA
Florida Heart Institute and Florida Hospital, Orlando, Florida, USA
MidCarolina Cardiology and Presbyterian Hospital, Charlotte, North Carolina, USA
|| Cedar-Sinai Medical Center and UCLA School of Medicine, Los Angeles, California, USA
¶ St. Josephs Hospital Health Center, Syracuse, New York, USA
** Medtronic Inc., Minneapolis, Minnesota, USA

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Figure 1 Cardiac compass report. The atrial pacing therapies were activated on January 20. The vertical dashed line indicates the last device interrogation. The atrial tachycardia (AT)/atrial fibrillation (AF) Patient Check indicates the days that the patient used his or her activator because of symptoms. The patient received the activator at the time of randomization. CV = cardioversion.
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Figure 2 An atrial tachycardia (AT) episode that was terminated by Ramp therapy. The graph shows the intervals between atrial (A-A) and ventricular (V-V) events at episode onset, detection, first therapy, and termination. The Ramp therapy was initiated 3.8 min after detection and resulted in the immediate termination of the atrial tachyarrhythmia. AF = atrial fibrillation.
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Figure 3 Histogram of atrial tachycardia/atrial fibrillation episode duration. The median episode frequency in each duration band was compared between the ON and OFF groups, and no significant differences were observed (p 0.17).
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Copyright © 2003 by the American College of Cardiology Foundation.