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Assessment of right ventricular perfusion after right coronary artery occlusion by myocardial contrast echocardiography

Hisashi Masugata, MD^*, Norihiro Fujita, MD^*, Isao Kondo, MD^*, Barry Peters, MD, Koji Ohmori, MD^*, Katsufumi Mizushige, MD, FACC^*, Masakazu Kohno, MD^* and Anthony N. DeMaria, MD, MACC^*,

^* Second Department of Internal Medicine, Kagawa Medical University, Kita-gun, Japan
Cardiovascular Division, University of California at San Diego, San Diego, California, USA

View larger version (47K): [in a new window]   Figure 1 Myocardial contrast echocardiography images at baseline (left) and during coronary occlusion (right). The blue line indicates the region of interest to measure video-intensity in the right ventricular (RV) wall for each image.

View larger version (78K): [in a new window]   Figure 2 Myocardial contrast echocardiography images at varying pulsing intervals during baseline and right coronary artery occlusion from dogs with mild (top) and severe (bottom) opacification defects.

View larger version (23K): [in a new window]   Figure 3 Plots of video-intensity (y-axis) versus pulsing interval (x-axis) from dogs shown in Figure 2, with mild (left) and severe (right) opacification defects.

View larger version (80K): [in a new window]   Figure 4 Risk area of the right coronary artery (RCA) delineated by blue dye staining for the slice corresponding to the imaging plane of myocardial contrast echocardiography in the same dogs as in Figures 2 and 3. Regions that were not stained by blue dye between arrows denote the RCA bed.

View larger version (30K): [in a new window]   Figure 5 Changes in right ventricular (RV) wall thickness (A), RV dimension (B), and myocardial contrast echocardiography-derived parameters (C, D, and E) produced by right coronary artery occlusion.

View larger version (18K): [in a new window]   Figure 6 Extent of risk area of an occluded right coronary artery (RCA) delineated by blue dye staining (left), changes in microsphere-derived myocardial blood flow (MBF) in the risk area (middle), and the percent of change in MBF produced by RCA occlusion (right).

View larger version (46K): [in a new window]   Figure 7 Correlation between myocardial contrast echocardiography-derived parameters (x-axis) and microsphere-derived myocardial blood flow (MBF) (y-axis).