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J Am Coll Cardiol, 2003; 41:1769-1775, doi:10.1016/S0735-1097(03)00333-4
© 2003 by the American College of Cardiology Foundation
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Predictive value of noninvasivelydetermined endothelial dysfunction for long-term cardiovascular events inpatients with peripheral vascular disease

Noyan Gokce, MD, FACC*, John F. Keaney, Jr, MD, FACC*, Liza M. Hunter, ANP*, Michael T. Watkins, MD{dagger}, Zoran S. Nedeljkovic, MD*, James O. Menzoian, MD{ddagger} and Joseph A. Vita, MD, FACC*,*

* Evans Department of Medicine and Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston, Massachusetts, USA
{dagger} Surgical Service, Massachusetts General Hospital, Boston, Massachusetts, USA
{ddagger} Department of Surgery, Boston University School of Medicine, Boston, Massachusetts, USA



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  		Figure 1 Kaplan-Meier plots showing survival according to brachial-artery flow-mediated dilation (FMD). The upper panel displays survival according to tertile of FMD. Overall, survival differed according to tertile of FMD (p = 0.0005). By multiple pairwise comparison, the survival curves for the lowest and middle tertiles did not differ (p = 0.87), but both differed from the highest tertile by log-rank test (p = 0.0003 and p = 0.0001, respectively). The middle panel displays survival for patients in the highest tertile and for the combination of the middle and lowest tertiles. The survival curves differed by log-rank test (p = 0.0001). In the lower panel, the analysis included only those events that occurred more than 30 days after vascular surgery and displays survival curves for patients in the highest tertile and for the combination of the middle and lowest tertiles. The survival curves differed by log-rank test (p = 0.006).

 




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