Pulse pressure and endothelial dysfunction in never-treated hypertensive patients
Roberto Ceravolo, MD*,
Raffaele Maio, MD*,
Arturo Pujia, MD*,
Angela Sciacqua, MD*,
Giorgio Ventura, MD*,
Maria C. Costa, MD*,
Giorgio Sesti, MD* and
Francesco Perticone, MD*,*
* Internal Medicine and Cardiovascular Diseases Unit, Department of Experimental and Clinical Medicine G. Salvatore, University Magna Græcia of Catanzaro, Catanzaro, Italy
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Figure 1 Blood pressure (bars) and peak percent increase in forearm blood flow (line) values by quartiles of pulse pressure are graphically reported. It is evident that forearm blood flow values progressively decrease from lower to upper quartile of pulse pressure. The picture also demonstrates the contribution of both systolic and diastolic blood pressure (dark zone) to increase in pulse pressure. Particularly, from lower to upper quartile of pulse pressure, systolic blood pressure increases by 17 mm Hg, whereas diastolic blood pressure decreases by 6 mm Hg.
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