Repeated intravascular ultrasound imaging in cardiac transplant recipients does not accelerate transplant coronary artery disease
Kumudha Ramasubbu, MD*,
Paul Schoenhagen, MD*,
Mohammed A. Balghith, MD*,
Johannes Brechtken, MD*,
Khaled M. Ziada, MD*,
Samir R. Kapadia, MD, FACC*,
Robert E. Hobbs, MD, FACC*,
Gustavo Rincon, MD, FACC*,
Steven E. Nissen, MD, FACC* and
E. Murat Tuzcu, MD, FACC*,*
* Department of Cardiology, The Cleveland Clinic Foundation, Cleveland, Ohio, USA

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Figure 1 Arterial diameter of the left anterior descending artery displayed by the Coronary Artery Surgery Study segment and the number of intravascular ultrasound (IVUS) exams. No significant difference was found among the diameters of arteries that had no IVUS exam versus those that underwent 1 to 6 exams.
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Figure 2 Arterial diameter of the left circumflex artery displayed by the Coronary Artery Surgery Study segment and the number of intravascular ultrasound (IVUS) exams. No significant difference was found among the diameters of arteries that had no IVUS exam versus those that underwent 1 to 6 exams.
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Figure 3 Arterial diameter of the right coronary artery displayed by the Coronary Artery Surgery Study segment and the number of intravascular ultrasound (IVUS) exams. No significant difference was found among the diameters of arteries that had no IVUS exam versus those that underwent 1 to 6 exams.
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Figure 4 Baseline and follow-up quantitative coronary angiography measurements (up to four years after cardiac transplantation) of proximal and distal diameters in arteries with previous intravascular ultrasound (IVUS) exams (n = 60) and without previous IVUS exams (n = 33). A significant decrease in proximal and distal vessel diameters could be demonstrated in the nonimaged and imaged arteries. However, the change in diameter between baseline and follow-up exams in nonimaged as well as imaged arteries was not statistically different (see p value). Diamond/solid line = imaged proximal; triangle/solid line = nonimaged proximal; diamond/dashed line = imaged distal; triangle/dashed line = nonimaged distal.
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