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Left ventricular diastolic dysfunction as a predictor of the first diagnosed nonvalvular atrial fibrillation in 840 elderly men and women

Teresa S. M. Tsang, MD, FACC^*,*, Bernard J. Gersh, MB, ChB, DPhil, FACC^*, Christopher P. Appleton, MD, A. Jamil Tajik, MD, FACC^*, Marion E. Barnes, MS^*, Kent R. Bailey, PhD, Jae K. Oh, MD, FACC^*, Cynthia Leibson, PhD, Samantha C. Montgomery, MS and James B. Seward, MD, FACC^*

^* Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, USA
Section of Biostatistics, Mayo Clinic, Rochester, Minnesota, USA
Section of Clinical Epidemiology, Mayo Clinic, Rochester, Minnesota, USA
Division of Cardiovascular Diseases, Mayo Clinic, Scottsdale, Arizona, USA

View larger version (25K): [in a new window]   Figure 1 Age-adjusted cumulative survival without nonvalvular atrial fibrillation (NVAF) by left atrial volume indexed to body surface area (LAVI).

View larger version (23K): [in a new window]   Figure 2 Age-adjusted cumulative survival without nonvalvular atrial fibrillation (NVAF) by diastolic function profile.

View larger version (20K): [in a new window]   Figure 3 Predictive power of four models (clinical with only clinical risk factors, clinical and left atrial [LA] volume, clinical and diastolic function profile, and clinical with LA volume and diastolic function profile) for nonvalvular atrial fibrillation.