This Article Abstract Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Pitzalis, M. V. Articles by Rizzon, P. Search for Related Content PubMed PubMed Citation Articles by Pitzalis, M. V. Articles by Rizzon, P.

Cardiac resynchronization therapy tailored by echocardiographic evaluation of ventricular asynchrony

Maria Vittoria Pitzalis, MD, PhD^*,*, Massimo Iacoviello, MD^*, Roberta Romito, MD, Francesco Massari, MD, Brian Rizzon, MD^*, Giovanni Luzzi, MD^*, Pietro Guida, MS^*, Andrea Andriani, MD^*, Filippo Mastropasqua, MD and Paolo Rizzon, MD^*

^* Institute of Cardiology, University of Bari, Bari, Italy
Cardiology, "S. Maugeri" Foundation, IRCCS, Cassano Murge, Bari, Italy

View larger version (106K): [in a new window]   Figure 1 Mono-dimensional short-axis view of the echocardiographic image taken at the level of the papillary muscles. Calculation of septal-to-posterior wall motion delay (SPWMD) obtained by measuring the shortest interval between the maximal posterior displacement of the septum (a) and the posterior wall (b).

View larger version (101K): [in a new window]   Figure 2 Two-dimensional apical four-chamber view of echocardiographic images. Left ventricular end-systolic volumes before (pre) device implantation (left images) and one month after cardiac resynchronization therapy (right images) in two different patients. (A) This patient had a prolonged pre-implantation septal-to-posterior wall motion delay (SPWMD) and a marked left ventricular end-systolic volume reduction after one month. (B) This patient had a short pre-implantation SPWMD and no reverse remodeling.

View larger version (19K): [in a new window]   Figure 3 (Top) The correlation between the baseline values of septal-to-posterior wall motion delay (SPWMD) and LVESVI. (Bottom) Correlation between baseline QRS duration and LVESVI. LVESVI = difference between post- and pre-implantation left ventricular end-systolic volumes indexed for body surface area.

View larger version (23K): [in a new window]   Figure 4 The receiver operating characteristic curves for septal-to-posterior wall motion delay (SPWMD), PQ interval, and QRS duration to predict reverse remodeling. The areas underlying SPWMD and QRS duration are statistically different.