Myocardial beta-adrenoceptor densityone month after acute myocardial infarctionpredicts left ventricular volumes at six months
Nicos Spyrou, BSc, MD, MRCP*,
Stuart D. Rosen, MA, MD, FESC, FACC, FRCP*,
Farzin Fath-Ordoubadi, BSc, MD, MRCP*,
Rohan Jagathesan, BSc, MRCP*,
Rodney Foale, FRCP*,
Jaspal S. Kooner, MD, FRCP* and
Paolo G. Camici, MD, FESC, FACC, FAHA, FRCP*,*
* Medical Research Council Clinical Sciences Centre and National Heart and Lung Institute, Faculty of Medicine, Imperial College, London, United Kingdom
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Figure 1 Regression line (n = 61) through individual patients’ end-systolic volume change (ESV) (values at six months divided by those at one week), plotted against the respective beta-adrenoceptor density as measured by positron emission tomography, one month post-acute myocardial infarction.
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Figure 2 Regression line (n = 61) through individual patients’ end-diastolic volume change (EDV) (values at six months divided by those at one week), plotted against the respective beta-adrenoceptor density as measured by positron emission tomography, one month post-acute myocardial infarction.
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Figure 3 Black bars = those patients (n = 41) whose left ventricular (LV) volumes were found to be decreased six months after infarction; White bars = those patients (n = 20) whose LV volumes were found to be increased six months after infarction. Beta-AR = myocardial beta-adrenoceptor density.
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