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Coronary atherosclerosis in diabetes mellitus

A population-based autopsy study

Tauqir Y. Goraya, MD, PhD^*, Cynthia L. Leibson, PhD^||, Pasquale J. Palumbo, MD, Susan A. Weston, MS, Jill M. Killian, BS, Eric A. Pfeifer, MD, Steven J. Jacobsen, MD, PhD^||, Robert L. Frye, MD^* and V.éronique L. Roger, MD, MPH^*,*

^* Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic Scottsdale and Rochester and Mayo Foundation, Rochester, Minnesota, USA
Division of Anatomic Pathology, Mayo Clinic Scottsdale and Rochester and Mayo Foundation, Rochester, Minnesota, USA
Division of Endocrinology and Internal Medicine, Mayo Clinic Scottsdale and Rochester and Mayo Foundation, Rochester, Minnesota, USA
Division of Biostatistics, Mayo Clinic Scottsdale and Rochester and Mayo Foundation, Rochester, Minnesota, USA
^|| Division of Epidemiology, Mayo Clinic Scottsdale and Rochester and Mayo Foundation, Rochester, Minnesota, USA

View larger version (24K): [in a new window]   Figure 1 Distribution of global coronary scores by diabetes and clinical coronary disease status. CHD = coronary heart disease; DM = diabetes mellitus.

View larger version (49K): [in a new window]   Figure 2 Prevalence of any high-grade or multivessel coronary atherosclerosis at autopsy by diabetes and clinical coronary disease status. Data are presented by age and gender categories. (Top) Prevalence of any high-grade coronary atherosclerosis for (A) men and (B) women. (Bottom) Prevalence of multivessel disease for (C) men and (D) women. The p values are for results of test for equality between groups, indicated by horizontal brackets. *p < 0.01. CAD = coronary artery disease.