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Relationship between obesity, insulin resistance, and coronary heart disease risk

Fahim Abbasi, MD^*, Byron William Brown, Jr, PhD, Cindy Lamendola, MSN, ANP^*, Tracey McLaughlin, MD^* and Gerald M. Reaven, MD^*,*

^* Department of Medicine, Stanford, California, USA
Department of Health Research and Policy, Stanford University School of Medicine, Stanford, California, USA

View larger version (32K): [in a new window]   Figure 1 Relationship between body mass index and steady-state plasma glucose.

View larger version (33K): [in a new window]   Figure 2 Graphic representation of the relationship between body mass index (BMI), steady-state plasma glucose, and coronary heart disk risk factors for regression model B. Dependent variables: coronary heart disease risk factors (age, systolic blood pressure, diastolic blood pressure, total cholesterol, triglycerides, high-density lipoprotein [HDL] cholesterol, low-density lipoprotein [LDL] cholesterol, glucose response, and insulin response). Independent variables: BMI, steady-state plasma glucose, and the interaction term. RB = multiple correlation coefficient for the analyses based on regression model B.