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Large artery stiffness predicts ischemic threshold in patients with coronary artery disease

Bronwyn A. Kingwell, PhD^*,*, Tamara K. Waddell, PhD^*, Tanya L. Medley, BAppSc^*, James D. Cameron, MD, MengSc and Anthony M. Dart, BChBM, DPhil^*

^* Alfred and Baker Medical Unit, Baker Medical Research Institute, Prahran, Victoria, Australia
Department of Electronic Engineering, Latrobe University, Bundoora, Victoria, Australia

View larger version (17K): [in a new window]   Figure 1 Univariate correlations between arterial stiffness indexes and time to ST-segment depression of 1.5 mm (time to ischemia). All data are adjusted to the mean age of the group (62 years) using the slope of the univariate relationship between each variable and age. The full regression equations for systemic arterial compliance (SAC), distensibility index (DI), and augmentation index (AI) are: time to ischemia = –7.47·age + 179·SAC + 738; time to ischemia = –7.26·age + 717·DI + 711; time to ischemia = –7.90·age – 2.53·AI + 910.